CSF Sample Requirements A minimum of 0.6ml clear and colourless CSF sample is required for CSF RT-QuIC analysis.Bloodstained CSF or samples with RCC > 1250 are not accepted as they invalidate the test.Elevated CSF total protein > 1g/L and CSF white cell count > 20 may interfere with the assay.The CSF sample should be frozen within 2-3 hours. A normal -20°C freezer is acceptable, but -70°C/-80°C is preferable. This article was published on 2025-03-27